100% agree! The creedmore works well on game by putting a bullet it in the lungs and it won't last long. I have no issues with that at all.
I personally like the bigger cartridges for taking steeply quartering away shots. Last year I would not believe I would have tagged a bull with a smaller caliber. Long story short, I had a tiny window in 7' shrub oak at 300 yards, all broadside shots had a cow elk behind him, and when they finally moved he was turning away.
I shot him extremely quartering away. It entered in through rear of stomach, went through paunch, browse, liver, lungs, and breaking the far side leg before exiting....about 4 ft of penetration. It was my only shot opportunity and luckily i had that 338 w/ 260 gr bullets......and he sure enough he collapsed like he was hit by a freight train.